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Web2 Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece. PMID: 29876887 DOI: 10.1007/978-1-4939-7868-7_1 Abstract The basic … WebThe first and earliest principle of evidence-based medicine indicated that a hierarchy of evidence exists. Not all evidence is the same. This principle became well known in the early 1990s as practising physicians learnt … WebRandomised Controlled Trials. Randomised controlled trials are often seen as the gold standard of epidemiological research, especially in clinical settings, and in this module you will learn why. You will learn the main design features of randomised clinical trials, why they are so important, and the difficulties and limitations in applying ... dutch love nepean